Clinical validation of an integrated risk assessment test incorporating genomic and non-genomic data for sporadic breast cancer in Colombia

Clinical validation of an integrated risk assessment test incorporating genomic and non-genomic data for sporadic breast cancer in Colombia

IntroductionBreast cancer risk arises from a complex interaction of genetic, environmental, and physiological factors. Integrating Polygenic Risk Scores (PRS) with clinical risk factors can enhance personalized risk prediction, especially in diverse populations like Colombia.ObjectiveTo evaluate the...

Full description

Saved in:
Bibliographic Details
Main Authors: Harvy Mauricio Velasco Parra, Danny Styvens Cardona, Cesar Augusto Buitrago, Melisa Naranjo Vanegas, Sebastián Gutiérrez Hincapié, Carolina Jaramillo Jaramillo, Alicia Maria Cock-Rada, Carolina Benavides Duque, Clara Patricia Piedrahita, Catalina Bustamante, Leonel Andrés González Niño, Jen Kintle, Scott Kulm, Alessandro Bolli, Paolo Di Dominico, Giordano Botta, George B. Busby, Juan Pablo Valencia-Arango
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Genetics
Subjects:
polygenic risk score
breast cancer
risk stratification
prediction
epidemiology
Colombia
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1556907/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2025.1556907/full

Similar Items