Laryngomalacia: Disease Presentation, Spectrum, and Management
Laryngomalacia is the most common cause of stridor in newborns, affecting 45–75% of all infants with congenital stridor. The spectrum of disease presentation, progression, and outcomes is varied. Identifying symptoms and patient factors that influence disease severity helps predict outcomes. Findin...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2012/753526 |
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| author | April M. Landry Dana M. Thompson |
| author_facet | April M. Landry Dana M. Thompson |
| author_sort | April M. Landry |
| collection | DOAJ |
| description | Laryngomalacia is the most common cause of stridor in newborns, affecting 45–75% of all infants with congenital stridor. The spectrum of disease presentation, progression, and outcomes is varied. Identifying symptoms and patient factors that influence disease severity helps predict outcomes.
Findings. Infants with stridor who do not have significant feeding-related symptoms can be managed expectantly without intervention. Infants with stridor and feeding-related symptoms benefit from acid suppression treatment. Those with additional symptoms of aspiration, failure to thrive, and consequences of airway obstruction and hypoxia require surgical intervention. The presence of an additional level of airway obstruction worsens symptoms and has a 4.5x risk of requiring surgical intervention, usually supraglottoplasty. The presence of medical comorbidities predicts worse symptoms. Summary. Most with laryngomalacia will have mild-to-moderate symptoms and not require surgical intervention. Those with gastroesophageal reflux and/or laryngopharyngeal reflux have symptom improvement from acid suppression therapy. Those with severe enough disease to require supraglottoplasty will have minimal complications and good outcomes if multiple medical comorbidities are not present. Identifying patient factors that influence disease severity is an important aspect of care provided to infants with laryngomalacia. |
| format | Article |
| id | doaj-art-ad1f6a94af674de7825acac6eab973b7 |
| institution | Kabale University |
| issn | 1687-9740 1687-9759 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Pediatrics |
| spelling | doaj-art-ad1f6a94af674de7825acac6eab973b72025-02-03T01:09:35ZengWileyInternational Journal of Pediatrics1687-97401687-97592012-01-01201210.1155/2012/753526753526Laryngomalacia: Disease Presentation, Spectrum, and ManagementApril M. Landry0Dana M. Thompson1Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic Arizona, Phoenix, AZ 85054, USADivision of Pediatric Otolaryngology, Department of Otorhinolaryngology, Head and Neck Surgery, Mayo Clinic Children’s Center and Mayo Eugenio Litta Children’s Hospital, Mayo Clinic Rochester, 200 First Street SW, Gonda 12, Rochester, MN 55905, USALaryngomalacia is the most common cause of stridor in newborns, affecting 45–75% of all infants with congenital stridor. The spectrum of disease presentation, progression, and outcomes is varied. Identifying symptoms and patient factors that influence disease severity helps predict outcomes. Findings. Infants with stridor who do not have significant feeding-related symptoms can be managed expectantly without intervention. Infants with stridor and feeding-related symptoms benefit from acid suppression treatment. Those with additional symptoms of aspiration, failure to thrive, and consequences of airway obstruction and hypoxia require surgical intervention. The presence of an additional level of airway obstruction worsens symptoms and has a 4.5x risk of requiring surgical intervention, usually supraglottoplasty. The presence of medical comorbidities predicts worse symptoms. Summary. Most with laryngomalacia will have mild-to-moderate symptoms and not require surgical intervention. Those with gastroesophageal reflux and/or laryngopharyngeal reflux have symptom improvement from acid suppression therapy. Those with severe enough disease to require supraglottoplasty will have minimal complications and good outcomes if multiple medical comorbidities are not present. Identifying patient factors that influence disease severity is an important aspect of care provided to infants with laryngomalacia.http://dx.doi.org/10.1155/2012/753526 |
| spellingShingle | April M. Landry Dana M. Thompson Laryngomalacia: Disease Presentation, Spectrum, and Management International Journal of Pediatrics |
| title | Laryngomalacia: Disease Presentation, Spectrum, and Management |
| title_full | Laryngomalacia: Disease Presentation, Spectrum, and Management |
| title_fullStr | Laryngomalacia: Disease Presentation, Spectrum, and Management |
| title_full_unstemmed | Laryngomalacia: Disease Presentation, Spectrum, and Management |
| title_short | Laryngomalacia: Disease Presentation, Spectrum, and Management |
| title_sort | laryngomalacia disease presentation spectrum and management |
| url | http://dx.doi.org/10.1155/2012/753526 |
| work_keys_str_mv | AT aprilmlandry laryngomalaciadiseasepresentationspectrumandmanagement AT danamthompson laryngomalaciadiseasepresentationspectrumandmanagement |