Neurturin Evokes MAPK-Dependent Upregulation of Egr4 and KCC2 in Developing Neurons
The K-Cl cotransporter KCC2 plays a crucial role in the functional development of GABAA-mediated responses rendering GABA hyperpolarizing in adult neurons. We have previously shown that BDNF upregulates KCC2 in immature neurons through the transcription factor Egr4. The effect of BDNF on Egr4 and KC...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2011/641248 |
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