Enhanced antibody responses in CD19-Cre mice

Abstract CD19-Cre is an important and widely used Cre-lox model for B cell-specific genetic manipulation in murine systems. Mice carrying one allele of CD19-Cre are, at the same time, rendered heterozygote for CD19, a crucial coreceptor of the B cell antigen receptor (BCR). As a result, CD19-Cre mic...

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Bibliographic Details
Main Authors: Diogo M. Cunha, Sara Hernández-Pérez, Pieta K. Mattila
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-83954-8
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