Rapid nongenomic estrogen signaling controls alcohol drinking behavior in mice

Rapid nongenomic estrogen signaling controls alcohol drinking behavior in mice

Abstract Ovarian-derived estrogen can signal non-canonically at membrane-associated receptors in the brain to rapidly regulate neuronal function. Early alcohol drinking confers greater risk for alcohol use disorder in women than men, and binge alcohol drinking is correlated with high estrogen levels...

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Main Authors: Lia J. Zallar, Jean K. Rivera-Irizarry, Peter U. Hamor, Irena Pigulevskiy, Ana-Sofia Rico Rozo, Hajar Mehanna, Dezhi Liu, Jacqueline P. Welday, Rebecca Bender, Joseph J. Asfouri, Olivia B. Levine, Mary Jane Skelly, Colleen K. Hadley, Kristopher M. Fecteau, Scottie Nelson, John Miller, Pasha Ghazal, Peter Bellotti, Ashna Singh, Lauren V. Hollmer, David W. Erikson, Jacob Geri, Kristen E. Pleil
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54737-6
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https://doi.org/10.1038/s41467-024-54737-6

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