Identification of biomarkers for knee osteoarthritis through clinical data and machine learning models

Identification of biomarkers for knee osteoarthritis through clinical data and machine learning models

Abstract Knee osteoarthritis (KOA) represents a progressive degenerative disorder characterized by the gradual erosion of articular cartilage. This study aimed to develop and validate biomarker-based predictive models for KOA diagnosis using machine learning techniques. Clinical data from 2594 sampl...

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Bibliographic Details
Main Authors: Wei Chen, Haotian Zheng, Binglin Ye, Tiefeng Guo, Yude Xu, Zhibin Fu, Xing Ji, Xiping Chai, Shenghua Li, Qiang Deng
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Knee osteoarthritis
Clinical data
Machine learning
Diagnostic performance
Online Access:https://doi.org/10.1038/s41598-025-85945-9
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https://doi.org/10.1038/s41598-025-85945-9

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