Current perspectives in drug targeting intrinsically disordered proteins and biomolecular condensates

Abstract Intrinsically disordered proteins (IDPs) and biomolecular condensates are critical for cellular processes and physiological functions. Abnormal biomolecular condensates can cause diseases such as cancer and neurodegenerative disorders. IDPs, including intrinsically disordered regions (IDRs)...

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Bibliographic Details
Main Authors: Caolitao Qin, Yun-Long Wang, Jian Zheng, Xiang-Bo Wan, Xin-Juan Fan
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Biology
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Online Access:https://doi.org/10.1186/s12915-025-02214-x
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