H3K9 post-translational modifications regulate epiblast/primitive endoderm specification in rabbit blastocysts

Abstract Post-translational modifications of histone H3 on lysine 9, specifically acetylation (H3K9ac) and tri-methylation (H3K9me3), play a critical role in regulating chromatin accessibility. However, the role of these modifications in lineage segregation in the mammalian blastocyst remains poorly...

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Main Authors: Wilhelm Bouchereau, Hong-Thu Pham, Worawalan Samruan, Van-Hong Vu, Thierry Joly, Marielle Afanassieff, Pierre Savatier, Rangsun Parnpai, Nathalie Beaujean
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Epigenetics & Chromatin
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Online Access:https://doi.org/10.1186/s13072-025-00568-8
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