Takotsubo Syndrome Following Status Epilepticus in a Heart Transplant Recipient: A Case Report

Introduction: Takotsubo syndrome (TTS) expresses transient wall motion abnormality of the left ventricle, reportedly induced by sympathetic overstimulation. Takotsubo syndrome is unlikely to be included in the differential diagnosis of heart transplant patients with sudden cardiac dysfunction given...

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Main Authors: Takeshi Shikama, Mio Shikama, Naoki Hayase, Kent Doi
Format: Article
Language:English
Published: eScholarship Publishing, University of California 2025-01-01
Series:Clinical Practice and Cases in Emergency Medicine
Online Access:https://escholarship.org/uc/item/7xz6g72m
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author Takeshi Shikama
Mio Shikama
Naoki Hayase
Kent Doi
author_facet Takeshi Shikama
Mio Shikama
Naoki Hayase
Kent Doi
author_sort Takeshi Shikama
collection DOAJ
description Introduction: Takotsubo syndrome (TTS) expresses transient wall motion abnormality of the left ventricle, reportedly induced by sympathetic overstimulation. Takotsubo syndrome is unlikely to be included in the differential diagnosis of heart transplant patients with sudden cardiac dysfunction given the complete denervation occurring during the transplantation. Case Report: In this case report we describe the case of a female heart transplant recipient who showed apical ballooning on an echocardiogram following status epilepticus. Detailed clinical examinations and her clinical course confirmed the diagnosis of TTS. An iodine-123 meta iodobenzylguanidine myocardial scintigraphy revealed partial cardiac sympathetic reinnervation in the transplanted heart. Conclusion: This case demonstrates that TTS can manifest itself even in a transplanted heart with partial sympathetic reinnervation.
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institution Kabale University
issn 2474-252X
language English
publishDate 2025-01-01
publisher eScholarship Publishing, University of California
record_format Article
series Clinical Practice and Cases in Emergency Medicine
spelling doaj-art-abe283a1e51e4b89be5ff6e47df91fa12025-02-04T17:35:19ZengeScholarship Publishing, University of CaliforniaClinical Practice and Cases in Emergency Medicine2474-252X2025-01-0191172010.5811/cpcem.41970cpcem-9-17Takotsubo Syndrome Following Status Epilepticus in a Heart Transplant Recipient: A Case ReportTakeshi Shikama0Mio Shikama1Naoki Hayase2Kent Doi3The University of Tokyo, Department of Emergency and Critical Care Medicine, Tokyo, JapanThe University of Tokyo, Department of Emergency and Critical Care Medicine, Tokyo, JapanThe University of Tokyo, Department of Emergency and Critical Care Medicine, Tokyo, JapanThe University of Tokyo, Department of Emergency and Critical Care Medicine, Tokyo, JapanIntroduction: Takotsubo syndrome (TTS) expresses transient wall motion abnormality of the left ventricle, reportedly induced by sympathetic overstimulation. Takotsubo syndrome is unlikely to be included in the differential diagnosis of heart transplant patients with sudden cardiac dysfunction given the complete denervation occurring during the transplantation. Case Report: In this case report we describe the case of a female heart transplant recipient who showed apical ballooning on an echocardiogram following status epilepticus. Detailed clinical examinations and her clinical course confirmed the diagnosis of TTS. An iodine-123 meta iodobenzylguanidine myocardial scintigraphy revealed partial cardiac sympathetic reinnervation in the transplanted heart. Conclusion: This case demonstrates that TTS can manifest itself even in a transplanted heart with partial sympathetic reinnervation.https://escholarship.org/uc/item/7xz6g72m
spellingShingle Takeshi Shikama
Mio Shikama
Naoki Hayase
Kent Doi
Takotsubo Syndrome Following Status Epilepticus in a Heart Transplant Recipient: A Case Report
Clinical Practice and Cases in Emergency Medicine
title Takotsubo Syndrome Following Status Epilepticus in a Heart Transplant Recipient: A Case Report
title_full Takotsubo Syndrome Following Status Epilepticus in a Heart Transplant Recipient: A Case Report
title_fullStr Takotsubo Syndrome Following Status Epilepticus in a Heart Transplant Recipient: A Case Report
title_full_unstemmed Takotsubo Syndrome Following Status Epilepticus in a Heart Transplant Recipient: A Case Report
title_short Takotsubo Syndrome Following Status Epilepticus in a Heart Transplant Recipient: A Case Report
title_sort takotsubo syndrome following status epilepticus in a heart transplant recipient a case report
url https://escholarship.org/uc/item/7xz6g72m
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AT mioshikama takotsubosyndromefollowingstatusepilepticusinahearttransplantrecipientacasereport
AT naokihayase takotsubosyndromefollowingstatusepilepticusinahearttransplantrecipientacasereport
AT kentdoi takotsubosyndromefollowingstatusepilepticusinahearttransplantrecipientacasereport