Galectin-9 induces IL-1β production as a key inflammatory cytokine in the acute myeloid leukemia cell line (U937)

Galectin-9 induces IL-1β production as a key inflammatory cytokine in the acute myeloid leukemia cell line (U937)

Background and purpose: T-cell immunoglobulin and mucin-domain containing protein-3 (TIM-3)/ galectin-9 (Gal-9)/ autocrine loop in myeloid leukemia stem cells provokes inflammation through the NF-κB signaling pathway, which is influential in the expression of inflammatory factors. Interleukin 1β (IL...

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Bibliographic Details
Main Authors: Nafiseh Behranvand, Farzad Nasri, Maryam Vakily Moghaddam, Mohammad Davoodzadeh Gholami, Elahe Safari, Nafiseh Esmaeil, Reza Falak
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-03-01
Series:Research in Pharmaceutical Sciences
Subjects:
aml
gal-9
inflammation
il-1β
nf-κb
Online Access:https://journals.lww.com/10.4103/RPS.RPS_234_23
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https://journals.lww.com/10.4103/RPS.RPS_234_23

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