Chikungunya Particle and RNA Induce Mechanical and Heat Hypersensitivities in a TRPV1-Dependent Manner

Chikungunya Particle and RNA Induce Mechanical and Heat Hypersensitivities in a TRPV1-Dependent Manner

Chikungunya virus (CHIKV), the causative agent of the chikungunya fever, is an alphavirus widely transmitted by the bite of the female mosquito of the genus <i>Aedes</i> sp., especially in tropical and subtropical regions. Brazil is the country most affected by the microorganism. CHIKV c...

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Main Authors: Liziane C. M. da Silva, Andressa C. dos Santos Maia, Nágila C. F. de Sousa, Catielen P. Pavi, Beatriz P. Savi, Seigo Nagashima, Samara Damasceno, Ayda H. Schneider, Lucas Z. Mascarin, João F. S. Rodrigues, Cinara R. A. V. Monteiro, Izabella T. Silva, Gislaine Fongaro, Valério Monteiro-Neto, Maria R. Q. Bomfim, Thiago M. Cunha, João de Sousa Valente, João B. Calixto, Lúcia de Noronha, Susan D. Brain, Elizabeth S. Fernandes
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biomolecules
Subjects:
Chikungunya
viral RNA
arthralgia
TRPV1
nociception
Online Access:https://www.mdpi.com/2218-273X/15/2/171
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