Effects of gut microbiota on cognitive impairment in Parkinson’s disease: a comprehensive Mendelian randomization and case–control study

Effects of gut microbiota on cognitive impairment in Parkinson’s disease: a comprehensive Mendelian randomization and case–control study

BackgroundIncreasing evidence suggests a potential role of the gut microbiota in Parkinson’s disease (PD). However, the relationship between the gut microbiome (GM) and PD dementia (PDD) remains debated, with their causal effects and underlying mechanisms not yet fully understood.MethodsUtilizing da...

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Bibliographic Details
Main Authors: Yukun Feng, Qi Chang, Hao Zhou, Wei Zhang, Ling Xie, Xueyang Deng, Tao Chen, Weiguo Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Microbiology
Subjects:
gut microbiota
Parkinson dementia disease
metabolites
causal effect
Mendelian randomization
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1620449/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1620449/full

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