A Turbo‐Charging System‐Like Contrast Agent for MRI‐Guided STING Pathway‐Activated Cancer Immunotherapy

A Turbo‐Charging System‐Like Contrast Agent for MRI‐Guided STING Pathway‐Activated Cancer Immunotherapy

Abstract To overcome the problems of Gd‐based contrast agents (GBCAs) (nephrotoxicity and brain deposition) and stimulator of interferon genes (STING) agonists (poor stability, low delivery efficiency, and potential toxicity), in this study, a Turbo‐charging system‐like GBCA is designed and construc...

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Main Authors: Bin Ren, Sihua Yan, Zongheng Li, Ya Huang, Haobin Cai, Jing Yang, Qingdeng Fan, Chunmei Chen, Fanchao Que, Guochao Wu, Lin Huang, Ruilong Zhou, Jiaoyang Zhu, Chenggong Yan, Gang Liu, Zheyu Shen, Shipeng Ning
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
cancer immunotherapy
Gd‐based contrast agents (GBCAs)
magnetic resonance imaging (MRI)
stimulator of interferon genes (STING)
turbo‐charging system‐like contrast agent (Turbo S)
Online Access:https://doi.org/10.1002/advs.202410432
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https://doi.org/10.1002/advs.202410432

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