Bayesian dynamic borrowing in group-sequential design for medical device studies

Abstract Background The integration of historical data into ongoing clinical trials through Bayesian Dynamic Borrowing offers significant advantages, including reduced sample size, trial duration, and associated costs. However, challenges such as ensuring exchangeability between historical and curre...

Full description

Saved in:
Bibliographic Details
Main Authors: Maria Vittoria Chiaruttini, Giulia Lorenzoni, Dario Gregori
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:https://doi.org/10.1186/s12874-025-02520-6
Tags: Add Tag
No Tags, Be the first to tag this record!