Far-red fluorescent genetically encoded calcium ion indicators

Far-red fluorescent genetically encoded calcium ion indicators

Abstract Genetically encoded calcium ion (Ca2+) indicators (GECIs) are widely-used molecular tools for functional imaging of Ca2+ dynamics and neuronal activities with single-cell resolution. Here we report the design and development of two far-red fluorescent GECIs, FR-GECO1a and FR-GECO1c, based o...

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Main Authors: Rochelin Dalangin, Bill Z. Jia, Yitong Qi, Abhi Aggarwal, Kenryo Sakoi, Mikhail Drobizhev, Rosana S. Molina, Ronak Patel, Ahmed S. Abdelfattah, Jihong Zheng, Daniel Reep, Jeremy P. Hasseman, The GENIE Project Team, Yufeng Zhao, Jiahui Wu, Kaspar Podgorski, Alison G. Tebo, Eric R. Schreiter, Thomas E. Hughes, Takuya Terai, Marie-Eve Paquet, Sean G. Megason, Adam E. Cohen, Yi Shen, Robert E. Campbell
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58485-z
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https://doi.org/10.1038/s41467-025-58485-z

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