Disrupted mucosal vascular barrier in eosinophilic esophagitis

Disrupted mucosal vascular barrier in eosinophilic esophagitis

Abstract Esophageal barrier has been investigated until now on the epithelial side only. Gut vascular barrier dysfunction has been recently implicated in a number of immune-mediated gastrointestinal disorders. We here characterized the esophageal vascular barrier (EVB) in eosinophilic esophagitis (E...

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Main Authors: Marco Vincenzo Lenti, Carlo Maria Rossi, Renato Cannizzaro, Giovanni Santacroce, Michela Lizier, Giulia Fornasa, Stefania Merli, Alessandra Pasini, Edoardo Vincenzo Savarino, Paola Spessotto, Michele Di Stefano, Aurelio Mauro, Alessandro Vanoli, Fabiana Zingone, Andrea Anderloni, Marietta Iacucci, Maria Rescigno, Antonio Di Sabatino
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Confocal laser endomicroscopy
Dupilumab
Esophageal mucosa
Plasmalemma vesicle-1
Reflux esophagitis
Online Access:https://doi.org/10.1038/s41598-025-09680-x
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https://doi.org/10.1038/s41598-025-09680-x

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