Slow gut transit increases the risk of Alzheimer’s disease: An integrated study of the bi-national cohort in South Korea and Japan and Alzheimer’s disease model mice

Slow gut transit increases the risk of Alzheimer’s disease: An integrated study of the bi-national cohort in South Korea and Japan and Alzheimer’s disease model mice

Introduction: Although the association between Alzheimer's disease (AD) and constipation is controversial, its causality and underlying mechanisms remain unknown. Objectives: To investigate the potential association between slow gut transit and AD using epidemiological data and a murine model....

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Bibliographic Details
Main Authors: Jiseung Kang, Myeongcheol Lee, Mincheol Park, Jibeom Lee, Sunjae Lee, Jaeyu Park, Ai Koyanagi, Lee Smith, Christa J. Nehs, Dong Keon Yon, Tae Kim
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Journal of Advanced Research
Subjects:
Alzheimer’s disease
Cohort
Constipation
Epidemiological data
Mouse model
Gut-brain axis
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123223003971
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