2dSpAn-Auto: an automated tool for analysis of two-dimensional dendritic spine images

Abstract Background Quantitative analysis of dendritic spine morphology and density is crucial for understanding synaptic plasticity and its role in neuropsychiatric disorders, including Alzheimer’s disease and schizophrenia. While both 3D and 2D approaches exist for spine analysis, 2D methods offer...

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Bibliographic Details
Main Authors: Shauvik Paul, Rahul Pramanick, Nirmal Das, Ewa Baczynska, Zeinab Bedrood, Tapabrata Chakraborti, Subhadip Basu, Jakub Wlodarczyk
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Bioinformatics
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Online Access:https://doi.org/10.1186/s12859-025-06179-0
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