Electrochemical Sensor Based on Carboxymethyl Cellulose-Coated Copper Nanoparticle Composite for Detection of Norfloxacin in Milk
A highly sensitive electrochemical sensor for the detection of norfloxacin (NFX) was constructed using CMC@Cu/CB composites, which were prepared from carboxymethyl cellulose (CMC)-coated copper nanoparticles (Cu NPs) and carbon black (CB). The structure and morphology of CMC@Cu/CB were characterized...
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| Main Author: | |
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| Format: | Article |
| Language: | English |
| Published: |
China Food Publishing Company
2025-01-01
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| Series: | Shipin Kexue |
| Subjects: | |
| Online Access: | https://www.spkx.net.cn/fileup/1002-6630/PDF/2025-46-1-021.pdf |
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| Summary: | A highly sensitive electrochemical sensor for the detection of norfloxacin (NFX) was constructed using CMC@Cu/CB composites, which were prepared from carboxymethyl cellulose (CMC)-coated copper nanoparticles (Cu NPs) and carbon black (CB). The structure and morphology of CMC@Cu/CB were characterized by scanning electron microscope (SEM), X-ray photoelectron spectroscopy (SPS), and X-ray diffraction (XRD). The CMC@Cu/CB/GCE sensor was prepared by drop-casting the composite suspension on the glassy carbon electrode (GCE) surface. The results showed that the CMC@Cu/CB/GCE sensor, which was in the form of uniformly dispersed spheres, had a good current response to NFX, with a linear range of 0.4–100.0 μmol/L and a limit of detection (LOD) of 0.24 μmol/L (RSN = 3). In addition, the modified electrode had good sensitivity and stability for the detection of NFX in real samples, and the spiked recoveries of NFX in milk extracts ranged from 98.8%–112.5%. Furthermore, thanks to the low price of raw materials used in the experimental process and the preparation extremely of low cost of the sensor, it is promising for actual applications. |
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| ISSN: | 1002-6630 |