Bezlotoxumab prevents extraintestinal organ damage induced by Clostridioides difficile infection

Bezlotoxumab prevents extraintestinal organ damage induced by Clostridioides difficile infection

Clostridioides difficile is the most common cause of infectious antibiotic-associated diarrhea, with disease mediated by two major toxins TcdA and TcdB. In severe cases, systemic disease complications may arise, resulting in fatal disease. Systemic disease in animal models has been described, with t...

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Bibliographic Details
Main Authors: Steven J. Mileto, Melanie L. Hutton, Sarah L. Walton, Antariksh Das, Lisa J. Ioannidis, Don Ketagoda, Kylie M. Quinn, Kate M. Denton, Diana S. Hansen, Dena Lyras
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Gut Microbes
Subjects:
Clostridioides difficile
toxin
epithelial damage
bacterial infection
systemic disease
colon damage
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2022.2117504
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https://www.tandfonline.com/doi/10.1080/19490976.2022.2117504

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