Microglial activation and hypothalamic structural plasticity in HFD obesity: insights from semaglutide and minocycline

High-fat diet (HFD)-induced microglial activation contributes to hypothalamic inflammation and obesity, but the mechanisms linking microglia to structural changes remain unclear. This study explored the role of microglia in impairing hypothalamic synaptic plasticity in diet-induced obesity mice and...

Full description

Saved in:
Bibliographic Details
Main Authors: Xi Rong, Fang Wei, Yuqi Jiang, Qintao Ma, Dongmei Wang, Jie Shen
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227524002414
Tags: Add Tag
No Tags, Be the first to tag this record!