Natural compounds may contribute in preventing SARS-CoV-2 infection: a narrative review

Coronavirus pandemic infection is the most important health issue worldwide. Coronavirus disease 2019 is a contagious disease characterized by severe acute respiratory syndrome coronavirus 2. To date, excluding the possibility of vaccination, against SARS-CoV-2 infection it is possible to act only w...

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Main Authors: Maria Eleonora Bizzoca, Stefania Leuci, Michele Davide Mignogna, Eleonora Lo Muzio, Vito Carlo Alberto Caponio, Lorenzo Lo Muzio
Format: Article
Language:English
Published: Tsinghua University Press 2022-09-01
Series:Food Science and Human Wellness
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Online Access:http://www.sciencedirect.com/science/article/pii/S221345302200043X
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author Maria Eleonora Bizzoca
Stefania Leuci
Michele Davide Mignogna
Eleonora Lo Muzio
Vito Carlo Alberto Caponio
Lorenzo Lo Muzio
author_facet Maria Eleonora Bizzoca
Stefania Leuci
Michele Davide Mignogna
Eleonora Lo Muzio
Vito Carlo Alberto Caponio
Lorenzo Lo Muzio
author_sort Maria Eleonora Bizzoca
collection DOAJ
description Coronavirus pandemic infection is the most important health issue worldwide. Coronavirus disease 2019 is a contagious disease characterized by severe acute respiratory syndrome coronavirus 2. To date, excluding the possibility of vaccination, against SARS-CoV-2 infection it is possible to act only with supportive care and non-virus-specific treatments in order to improve the patient's symptoms. Pharmaceutical industry is investigating effects of medicinal plants, phytochemical extracts and aromatic herbs to find out natural substances which may act as antiviral drugs. Several studies have revealed how these substances may interfere with the viral life cycle, viral entry, replication, assembly or discharge, as well as virus-specific host targets or stimulating the host immune system, reducing oxidative stress and inflammatory response. A natural compound can be used as a prophylaxis by people professionally exposed to the risk of contagion and/or positive patients not in intensive care. The aim of this paper is to perform a narrative review of current literature in order to summarize the most studied natural compounds and their modes of action.
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spelling doaj-art-a9fc95cf9d9b4a548b674285fd8eca1d2025-02-03T02:27:47ZengTsinghua University PressFood Science and Human Wellness2213-45302022-09-0111511341142Natural compounds may contribute in preventing SARS-CoV-2 infection: a narrative reviewMaria Eleonora Bizzoca0Stefania Leuci1Michele Davide Mignogna2Eleonora Lo Muzio3Vito Carlo Alberto Caponio4Lorenzo Lo Muzio5Department of Clinical and Experimental Medicine, University of Foggia, Foggia 71122, ItalyDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, Naples 80131, ItalyDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, Naples 80131, ItalyDepartment of Neuroscience and Rehabilitation, University of Ferrara, Ferrara 44121, ItalyDepartment of Clinical and Experimental Medicine, University of Foggia, Foggia 71122, ItalyDepartment of Clinical and Experimental Medicine, University of Foggia, Foggia 71122, Italy; C.I.N.B.O. (Consorzio Interuniversitario Nazionale per la Bio-Oncologia), Chieti 66100, Italy; Corresponding Author at: Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy., fax 0039 0881 588081.Coronavirus pandemic infection is the most important health issue worldwide. Coronavirus disease 2019 is a contagious disease characterized by severe acute respiratory syndrome coronavirus 2. To date, excluding the possibility of vaccination, against SARS-CoV-2 infection it is possible to act only with supportive care and non-virus-specific treatments in order to improve the patient's symptoms. Pharmaceutical industry is investigating effects of medicinal plants, phytochemical extracts and aromatic herbs to find out natural substances which may act as antiviral drugs. Several studies have revealed how these substances may interfere with the viral life cycle, viral entry, replication, assembly or discharge, as well as virus-specific host targets or stimulating the host immune system, reducing oxidative stress and inflammatory response. A natural compound can be used as a prophylaxis by people professionally exposed to the risk of contagion and/or positive patients not in intensive care. The aim of this paper is to perform a narrative review of current literature in order to summarize the most studied natural compounds and their modes of action.http://www.sciencedirect.com/science/article/pii/S221345302200043XNatural compoundsSARS-CoV-2COVID-19PreventionInfectious diseasePhytochemicals
spellingShingle Maria Eleonora Bizzoca
Stefania Leuci
Michele Davide Mignogna
Eleonora Lo Muzio
Vito Carlo Alberto Caponio
Lorenzo Lo Muzio
Natural compounds may contribute in preventing SARS-CoV-2 infection: a narrative review
Food Science and Human Wellness
Natural compounds
SARS-CoV-2
COVID-19
Prevention
Infectious disease
Phytochemicals
title Natural compounds may contribute in preventing SARS-CoV-2 infection: a narrative review
title_full Natural compounds may contribute in preventing SARS-CoV-2 infection: a narrative review
title_fullStr Natural compounds may contribute in preventing SARS-CoV-2 infection: a narrative review
title_full_unstemmed Natural compounds may contribute in preventing SARS-CoV-2 infection: a narrative review
title_short Natural compounds may contribute in preventing SARS-CoV-2 infection: a narrative review
title_sort natural compounds may contribute in preventing sars cov 2 infection a narrative review
topic Natural compounds
SARS-CoV-2
COVID-19
Prevention
Infectious disease
Phytochemicals
url http://www.sciencedirect.com/science/article/pii/S221345302200043X
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