Enhanced dynorphin expression and secretion in pancreatic beta-cells under hyperglycemic conditions

Objective: Dynorphin, an endogenous opioid peptide predominantly expressed in the central nervous system and involved in stress response, pain, and addiction, has intrigued researchers due to its expression in pancreatic β-cells. In this study, we aimed to characterize dynorphin expression in mouse...

Full description

Saved in:
Bibliographic Details
Main Authors: Miranda Movahed, Ruy A. Louzada, Manuel Blandino-Rosano
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877824002199
Tags: Add Tag
No Tags, Be the first to tag this record!