Correlation analysis of circulating PCDH17 DNA methylation changes with rheumatoid arthritis patients

Correlation analysis of circulating PCDH17 DNA methylation changes with rheumatoid arthritis patients

Abstract Analyze the correlation between the DNA methylation levels of Protocadherin 17 (PCDH17) cg03865667 and rheumatoid arthritis (RA), and evaluate its potential as a biomarker for diagnosing RA. Peripheral blood samples were collected from a cohort of 370 individuals, comprising patients diagno...

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Main Authors: Fuyu Zhao, Mi Zhou, Jia Liu, Cen Chang, Ping Jiang, Kai Wei, Jianan Zhao, Yu Shan, Yixin Zheng, Yiming Shi, Yunshen Li, Yuejuan Zheng, Qianqian Li, Lei Wang, Huanru Qu, Liangjing Lv, Shicheng Guo, Xinliang Lv, Qi Zhu, Dongyi He
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Rheumatoid arthritis
DNA methylation
Protocadherin 17
Biomarker
Correlation analysis
Online Access:https://doi.org/10.1038/s41598-025-02236-z
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https://doi.org/10.1038/s41598-025-02236-z

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