Robust intrapulmonary CD8 T cell responses and protection with an attenuated N1L deleted vaccinia virus.

<h4>Background</h4>Vaccinia viruses have been used as a model for viral disease and as a protective live vaccine.<h4>Methodology and principal findings</h4>We investigated the immunogenicity of an attenuated strain of vaccinia virus engineered to inactivate the N1L gene (vGK5...

Full description

Saved in:
Bibliographic Details
Main Authors: Anuja Mathew, Joel O'Bryan, William Marshall, Girish J Kotwal, Masanori Terajima, Sharone Green, Alan L Rothman, Francis A Ennis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-10-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0003323&type=printable
Tags: Add Tag
No Tags, Be the first to tag this record!