Ketamine induced gut microbiota dysbiosis and barrier and hippocampal dysfunction in rats

Summary: The microbiota-gut-brain axis (MGBA) plays a pivotal role in drug addiction. However, the pathophysiological mechanism of MGBA in ketamine addiction remains elusive. The present study investigated the ketamine-induced gut microbiota disorders, intestinal barrier dysfunction, and the alterat...

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Main Authors: Lei Xie, Zelin Zhuang, Baowen Guo, Yuehua Huang, Xiaoyan Shi, Zikai Huang, Ziquan Xu, Yanbin Chen, Yuyin Cao, Yanmin Zheng, Renhua Wu, Shuhua Ma
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224023149
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