Effects of Eleclazine (GS6615) on the proarrhythmic electrophysiological changes induced by myocardial stretch
PurposeMyocardial stretch is a proarrhythmic factor. Eleclazine (GS6615) is a late sodium current (INaL) inhibitor that has shown protective effects against arrhythmias in various experimental models. Data on its effects during myocardial stretch are lacking. The aim of this study was to investigate...
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| Main Authors: | Francisco J. Chorro, Luis Such-Miquel, Samuel Cuñat, Oscar Arias-Mutis, Patricia Genovés, Manuel Zarzoso, Antonio Alberola, Luis Such-Belenguer, Irene Del Canto |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Physiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2025.1525836/full |
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