Eco-friendly synthesis of silver nanoparticles: Enhancing optimization reaction, characterization, and antimicrobial properties with Lantana camara from geothermal area
Green synthesis methods for producing silver nanoparticles (AgNPs) have garnered significant attention for their potential in medical applications. Despite the known potential of Lantana camara in AgNP synthesis, there is a lack of studies investigating its application when grown in extreme geotherm...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | South African Journal of Chemical Engineering |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1026918524001306 |
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| author | Pati Kemala Rinaldi Idroes Khairan Khairan Muliadi Ramli Binawati Ginting Zuchra Helwani Rifki Aulia Ghazi Mauer Idroes Muhammad Yusuf Rustam Efendi |
| author_facet | Pati Kemala Rinaldi Idroes Khairan Khairan Muliadi Ramli Binawati Ginting Zuchra Helwani Rifki Aulia Ghazi Mauer Idroes Muhammad Yusuf Rustam Efendi |
| author_sort | Pati Kemala |
| collection | DOAJ |
| description | Green synthesis methods for producing silver nanoparticles (AgNPs) have garnered significant attention for their potential in medical applications. Despite the known potential of Lantana camara in AgNP synthesis, there is a lack of studies investigating its application when grown in extreme geothermal environments, which may influence the properties and efficacy of the synthesized nanoparticles. This research aimed to fabricate AgNPs utilizing aqueous extract from L. camara, a plant growing in an extreme geothermal manifestation area. Another aim of this study is to evaluate their antimicrobial activity. Qualitative and quantitative phytochemical analyses of the plant's leaves were also conducted. Reaction optimization was performed using response surface methodology (RSM), employing a central composite design (CCD) approach. The characterization of AgNPs involved UV–vis spectroscopy, FTIR, SEM-EDX, and PSA. The antimicrobial testing was conducted against Gram-positive bacterium (S. aureus), Gram-negative bacterium (E. coli), and the fungus (C. albicans). The phytochemicals analysis revealed that the L. camara leaf extract contains flavonoids, phenolics, saponins, tannins, and steroids, lacking alkaloids and terpenoids, with total phenolic and flavonoid contents of 11.94 mg (GAE/g) and 6.70 mg (QE/g), respectively. The AgNPs exhibited a spherical shape with a surface plasmon resonance (SPR) peak at a wavelength of 417 nm, and the smallest particle size measured was 44 nm. Based on FTIR analysis, AgNPs have functional groups such as OH, NH, CC, and CH that were identified as groups involved in the reduction of Ag+ to Ag0 during the green synthesis of AgNPs. The AgNPs demonstrated the lowest antifungal activity against C. albicans. In summary, the aqueous leaf extract of L. camara from geothermal manifestation areas can serve as a bioreductant for AgNPs, exhibiting higher antibacterial activity against Gram-positive bacteria compared to Gram-negative ones. |
| format | Article |
| id | doaj-art-a8fab2996edf4f4db1d3dd7d4dc116ec |
| institution | Kabale University |
| issn | 1026-9185 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | South African Journal of Chemical Engineering |
| spelling | doaj-art-a8fab2996edf4f4db1d3dd7d4dc116ec2025-01-19T06:24:17ZengElsevierSouth African Journal of Chemical Engineering1026-91852025-01-01515767Eco-friendly synthesis of silver nanoparticles: Enhancing optimization reaction, characterization, and antimicrobial properties with Lantana camara from geothermal areaPati Kemala0Rinaldi Idroes1Khairan Khairan2Muliadi Ramli3Binawati Ginting4Zuchra Helwani5Rifki Aulia6Ghazi Mauer Idroes7Muhammad Yusuf8Rustam Efendi9Graduate School of Mathematics and Applied Sciences, Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia; Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia; Pusat Riset Obat Herbal Universitas Syiah Kuala, Banda Aceh 23111, Indonesia; Corresponding author at: Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia; Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia; Pusat Riset Obat Herbal Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaDepartment of Chemical Engineering, Universitas Riau, Pekanbaru 28293, IndonesiaDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaGraduate School of Mathematics and Applied Sciences, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia; Department of Occupational Health and Safety, Faculty of Health Science, Universitas Abulyatama, Aceh Besar 23372, IndonesiaDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh 23111, IndonesiaGreen synthesis methods for producing silver nanoparticles (AgNPs) have garnered significant attention for their potential in medical applications. Despite the known potential of Lantana camara in AgNP synthesis, there is a lack of studies investigating its application when grown in extreme geothermal environments, which may influence the properties and efficacy of the synthesized nanoparticles. This research aimed to fabricate AgNPs utilizing aqueous extract from L. camara, a plant growing in an extreme geothermal manifestation area. Another aim of this study is to evaluate their antimicrobial activity. Qualitative and quantitative phytochemical analyses of the plant's leaves were also conducted. Reaction optimization was performed using response surface methodology (RSM), employing a central composite design (CCD) approach. The characterization of AgNPs involved UV–vis spectroscopy, FTIR, SEM-EDX, and PSA. The antimicrobial testing was conducted against Gram-positive bacterium (S. aureus), Gram-negative bacterium (E. coli), and the fungus (C. albicans). The phytochemicals analysis revealed that the L. camara leaf extract contains flavonoids, phenolics, saponins, tannins, and steroids, lacking alkaloids and terpenoids, with total phenolic and flavonoid contents of 11.94 mg (GAE/g) and 6.70 mg (QE/g), respectively. The AgNPs exhibited a spherical shape with a surface plasmon resonance (SPR) peak at a wavelength of 417 nm, and the smallest particle size measured was 44 nm. Based on FTIR analysis, AgNPs have functional groups such as OH, NH, CC, and CH that were identified as groups involved in the reduction of Ag+ to Ag0 during the green synthesis of AgNPs. The AgNPs demonstrated the lowest antifungal activity against C. albicans. In summary, the aqueous leaf extract of L. camara from geothermal manifestation areas can serve as a bioreductant for AgNPs, exhibiting higher antibacterial activity against Gram-positive bacteria compared to Gram-negative ones.http://www.sciencedirect.com/science/article/pii/S1026918524001306Lantana camaraGeothermal zoneResponse surface methodologyAntibacterialAntifungalMedicinal plant |
| spellingShingle | Pati Kemala Rinaldi Idroes Khairan Khairan Muliadi Ramli Binawati Ginting Zuchra Helwani Rifki Aulia Ghazi Mauer Idroes Muhammad Yusuf Rustam Efendi Eco-friendly synthesis of silver nanoparticles: Enhancing optimization reaction, characterization, and antimicrobial properties with Lantana camara from geothermal area South African Journal of Chemical Engineering Lantana camara Geothermal zone Response surface methodology Antibacterial Antifungal Medicinal plant |
| title | Eco-friendly synthesis of silver nanoparticles: Enhancing optimization reaction, characterization, and antimicrobial properties with Lantana camara from geothermal area |
| title_full | Eco-friendly synthesis of silver nanoparticles: Enhancing optimization reaction, characterization, and antimicrobial properties with Lantana camara from geothermal area |
| title_fullStr | Eco-friendly synthesis of silver nanoparticles: Enhancing optimization reaction, characterization, and antimicrobial properties with Lantana camara from geothermal area |
| title_full_unstemmed | Eco-friendly synthesis of silver nanoparticles: Enhancing optimization reaction, characterization, and antimicrobial properties with Lantana camara from geothermal area |
| title_short | Eco-friendly synthesis of silver nanoparticles: Enhancing optimization reaction, characterization, and antimicrobial properties with Lantana camara from geothermal area |
| title_sort | eco friendly synthesis of silver nanoparticles enhancing optimization reaction characterization and antimicrobial properties with lantana camara from geothermal area |
| topic | Lantana camara Geothermal zone Response surface methodology Antibacterial Antifungal Medicinal plant |
| url | http://www.sciencedirect.com/science/article/pii/S1026918524001306 |
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