Efficacy of tranexamic acid in improving visual clarity and operative time of arthroscopic rotator cuff repair: A systematic review and meta-analysis
Objective: The aim of this study was to examine if tranexamic acid (TXA) can assist in improving outcomes of arthroscopic rotator cu! repair (RCR). Methods: The databases of PubMed, Embase, Web of Science, CENTRAL, and Scopus were searched for all types of studies examining the e"cacy of TXA...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
AVES
2024-11-01
|
| Series: | Acta Orthopaedica et Traumatologica Turcica |
| Online Access: | https://www.aott.org.tr/en/efficacy-of-tranexamic-acid-in-improving-visual-clarity-and-operative-time-of-arthroscopic-rotator-cuff-repair-a-systematic-review-and-meta-analysis-137432 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832545116638674944 |
|---|---|
| author | Yushun Qian Anqing Jiang Jun Yan Shouchun Zhang Siqiang Zhu |
| author_facet | Yushun Qian Anqing Jiang Jun Yan Shouchun Zhang Siqiang Zhu |
| author_sort | Yushun Qian |
| collection | DOAJ |
| description | Objective: The aim of this study was to examine if tranexamic acid (TXA) can assist in improving outcomes of arthroscopic rotator cu! repair (RCR).
Methods: The databases of PubMed, Embase, Web of Science, CENTRAL, and Scopus were searched for all types of studies examining the e"cacy of TXA for arthroscopic RCR. Twelve studies, 10 randomized controlled trials (RCTs), and 2 retrospective studies were considered eligible.
Results: Meta-analysis of only 2 studies using a visual clarity grading system showed better visualization with the use of TXA. A similar di!erence was noted for studies using the visual analog scale. Operating time was not significantly di!erent between the groups, but subgroup analysis of RCTs demonstrated reduced operating time with TXA. Meta-analysis showed no di!erence in 24-hour pain scores between TXA and control groups. Qualitative assessment of studies for blood loss showed no significant e!ect of TXA. No major complications were reported in any of the studies.
Conclusion: This study has pooled evidence suggesting that TXA can improve visual clarity in arthroscopic RCR and may also result in a reduction in operating time. TXA does not seem to reduce blood loss or 24-hour postoperative pain scores.
Level of Evidence: Level II, Therapeutic Study. |
| format | Article |
| id | doaj-art-a8cb8134bf4346ef8034fc7e3e0ca7dc |
| institution | Kabale University |
| issn | 1017-995X |
| language | English |
| publishDate | 2024-11-01 |
| publisher | AVES |
| record_format | Article |
| series | Acta Orthopaedica et Traumatologica Turcica |
| spelling | doaj-art-a8cb8134bf4346ef8034fc7e3e0ca7dc2025-02-03T08:25:16ZengAVESActa Orthopaedica et Traumatologica Turcica1017-995X2024-11-0158631832510.5152/j.aott.2024.24008Efficacy of tranexamic acid in improving visual clarity and operative time of arthroscopic rotator cuff repair: A systematic review and meta-analysisYushun Qian0https://orcid.org/0009-0000-3309-9746Anqing Jiang1https://orcid.org/0000-0002-2938-0620Jun Yan2https://orcid.org/0009-0001-6412-9351Shouchun Zhang3https://orcid.org/0009-0001-1550-0310Siqiang Zhu4Department of Orthopedics, The Second People’s Hospital of Xiangcheng District, Suzhou, ChinaDepartment of Orthopedics, The Second People’s Hospital of Xiangcheng District, Suzhou, ChinaDepartment of Orthopedics, The Second People’s Hospital of Xiangcheng District, Suzhou, China Department of Anesthesiology, The Second People’s Hospital of Xiangcheng District, Suzhou, China Department of Anesthesiology, The Second People’s Hospital of Xiangcheng District, Suzhou, China Objective: The aim of this study was to examine if tranexamic acid (TXA) can assist in improving outcomes of arthroscopic rotator cu! repair (RCR). Methods: The databases of PubMed, Embase, Web of Science, CENTRAL, and Scopus were searched for all types of studies examining the e"cacy of TXA for arthroscopic RCR. Twelve studies, 10 randomized controlled trials (RCTs), and 2 retrospective studies were considered eligible. Results: Meta-analysis of only 2 studies using a visual clarity grading system showed better visualization with the use of TXA. A similar di!erence was noted for studies using the visual analog scale. Operating time was not significantly di!erent between the groups, but subgroup analysis of RCTs demonstrated reduced operating time with TXA. Meta-analysis showed no di!erence in 24-hour pain scores between TXA and control groups. Qualitative assessment of studies for blood loss showed no significant e!ect of TXA. No major complications were reported in any of the studies. Conclusion: This study has pooled evidence suggesting that TXA can improve visual clarity in arthroscopic RCR and may also result in a reduction in operating time. TXA does not seem to reduce blood loss or 24-hour postoperative pain scores. Level of Evidence: Level II, Therapeutic Study.https://www.aott.org.tr/en/efficacy-of-tranexamic-acid-in-improving-visual-clarity-and-operative-time-of-arthroscopic-rotator-cuff-repair-a-systematic-review-and-meta-analysis-137432 |
| spellingShingle | Yushun Qian Anqing Jiang Jun Yan Shouchun Zhang Siqiang Zhu Efficacy of tranexamic acid in improving visual clarity and operative time of arthroscopic rotator cuff repair: A systematic review and meta-analysis Acta Orthopaedica et Traumatologica Turcica |
| title | Efficacy of tranexamic acid in improving visual clarity and operative time of arthroscopic rotator cuff repair: A systematic review and meta-analysis |
| title_full | Efficacy of tranexamic acid in improving visual clarity and operative time of arthroscopic rotator cuff repair: A systematic review and meta-analysis |
| title_fullStr | Efficacy of tranexamic acid in improving visual clarity and operative time of arthroscopic rotator cuff repair: A systematic review and meta-analysis |
| title_full_unstemmed | Efficacy of tranexamic acid in improving visual clarity and operative time of arthroscopic rotator cuff repair: A systematic review and meta-analysis |
| title_short | Efficacy of tranexamic acid in improving visual clarity and operative time of arthroscopic rotator cuff repair: A systematic review and meta-analysis |
| title_sort | efficacy of tranexamic acid in improving visual clarity and operative time of arthroscopic rotator cuff repair a systematic review and meta analysis |
| url | https://www.aott.org.tr/en/efficacy-of-tranexamic-acid-in-improving-visual-clarity-and-operative-time-of-arthroscopic-rotator-cuff-repair-a-systematic-review-and-meta-analysis-137432 |
| work_keys_str_mv | AT yushunqian efficacyoftranexamicacidinimprovingvisualclarityandoperativetimeofarthroscopicrotatorcuffrepairasystematicreviewandmetaanalysis AT anqingjiang efficacyoftranexamicacidinimprovingvisualclarityandoperativetimeofarthroscopicrotatorcuffrepairasystematicreviewandmetaanalysis AT junyan efficacyoftranexamicacidinimprovingvisualclarityandoperativetimeofarthroscopicrotatorcuffrepairasystematicreviewandmetaanalysis AT shouchunzhang efficacyoftranexamicacidinimprovingvisualclarityandoperativetimeofarthroscopicrotatorcuffrepairasystematicreviewandmetaanalysis AT siqiangzhu efficacyoftranexamicacidinimprovingvisualclarityandoperativetimeofarthroscopicrotatorcuffrepairasystematicreviewandmetaanalysis |