In vitro and in vivo study of concentrated growth factor (CGF) mediating macrophage polarization in bone defect repair

In vitro and in vivo study of concentrated growth factor (CGF) mediating macrophage polarization in bone defect repair

Concentrated growth factor (CGF) is widely applied in clinical practice, but whether it has bone promoting effects and its mechanism of action are still the focus of discussion. In this study, in vitro experiments demonstrate that CGF can promote the expression of Arg-1 in BMDM cells, facilitating t...

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Bibliographic Details
Main Authors: Deng xin, Zheng Junwen, Zou Jiacheng, Xun Qiongyu, He Huanzong, Li peng, Liao juan
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Regenerative Therapy
Subjects:
CGF
Macrophages
Bone regeneration
JAK/STAT
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320425000896
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