Antithrombin supplementation to prevent venous thromboembolism: A case of hereditary antithrombin deficiency with increased antithrombin clearance during pregnancy and peripartum

Antithrombin supplementation to prevent venous thromboembolism: A case of hereditary antithrombin deficiency with increased antithrombin clearance during pregnancy and peripartum

Hereditary antithrombin deficiency (HATD) is an autosomal dominant disorder that significantly increases the risk of venous thromboembolism (VTE) during pregnancy. Based on our experience with three previous cases and the Japanese clinical guidelines, we manage high-risk VTE in pregnant women with H...

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Main Authors: Ayako Kaneda-Takeuchi, Tomoaki Oda, Mei Kitamoto, Emiyu Fujiwara, Kenta Kawai, Megumi Narumi, Yoshimasa Horikoshi, Masako Matsumoto, Yukiko Kohmura-Kobayashi, Naomi Furuta-Isomura, Toshiyuki Uchida, Kazunao Suzuki, Naohiro Kanayama, Hiroaki Itoh, Naoaki Tamura
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Thrombosis Update
Subjects:
Abortion
Antithrombin clearance
Hereditary antithrombin deficiency
Placental abruption
Pregnancy
Venous thromboembolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2666572725000148
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