Magnesium Isoglycyrrhizinate Alleviates Alectinib-Induced Hepatotoxicity by Inhibiting Mitochondrial Damage-Mediated Pyroptosis

Magnesium Isoglycyrrhizinate Alleviates Alectinib-Induced Hepatotoxicity by Inhibiting Mitochondrial Damage-Mediated Pyroptosis

Yizhang Chen,1,2,* Chenxiang Wang,1,* Yuna Wu,3,* Yuhan Zeng,1,4 Shangjing Xie,5 Jialu Weng,5 Lei Guo,1,2 Jing Fu,1 Tao Zhou,1 Xiuhua Zhang,4 Ziye Zhou4,5 1Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, Peop...

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Main Authors: Chen Y, Wang C, Wu Y, Zeng Y, Xie S, Weng J, Guo L, Fu J, Zhou T, Zhang X, Zhou Z
Format: Article
Language:English
Published: Dove Medical Press 2025-07-01
Series:Drug Design, Development and Therapy
Subjects:
alectinib
mitochondria damage
oxidative stress
pyroptosis
magnesium isoglycyrrhizinate
Online Access:https://www.dovepress.com/magnesium-isoglycyrrhizinate-alleviates-alectinib-induced-hepatotoxici-peer-reviewed-fulltext-article-DDDT
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https://www.dovepress.com/magnesium-isoglycyrrhizinate-alleviates-alectinib-induced-hepatotoxici-peer-reviewed-fulltext-article-DDDT

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