Pediatric brain tumor patients display altered immune activation and reduced lymphopoiesis at the onset of disease

Pediatric brain tumor patients display altered immune activation and reduced lymphopoiesis at the onset of disease

Abstract Optimal immune function is crucial in preventing cancer development and growth and for the success of anti-cancer therapies. Here, we characterized the peripheral immunological status of 83 steroids-naïve pediatric patients with central nervous system neoplasia at the disease onset. Tumors...

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Main Authors: Marco Rosichini, Giada Del Baldo, Carmen Dolores De Luca, Francesca Benini, Shirley Genah, Maria Vinci, Alfredo Cerimele, Marianna Coccetti, Sara Flamini, Rita Carsetti, Antonella Cacchione, Andrea Carai, Angela Mastronuzzi, Franco Locatelli, Enrico Velardi
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-024-00755-y
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https://doi.org/10.1038/s41698-024-00755-y

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