Identification of ageing-associated gene signatures in heart failure with preserved ejection fraction by integrated bioinformatics analysis and machine learning

Identification of ageing-associated gene signatures in heart failure with preserved ejection fraction by integrated bioinformatics analysis and machine learning

The incidence of heart failure with preserved ejection fraction (HFpEF) increases with the ageing of populations. This study aimed to explore ageing-associated gene signatures in HFpEF to develop new diagnostic biomarkers and provide new insights into the underlying mechanisms of HFpEF. Mice were su...

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Bibliographic Details
Main Authors: Guoxing Li, Qingju Zhou, Ming Xie, Boying Zhao, Keyu Zhang, Yuan Luo, Lingwen Kong, Diansa Gao, Yongzheng Guo
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-07-01
Series:Genes and Diseases
Subjects:
Ageing
Bioinformatics analysis
HFpEF
Immune dysfunction
Machine learning
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304224002757
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http://www.sciencedirect.com/science/article/pii/S2352304224002757

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