The Association of VDR/FokI Gene Polymorphism and Protein Expression With Histopathological Alterations in Patients With Thyroid Colloid Nodule

The Association of VDR/FokI Gene Polymorphism and Protein Expression With Histopathological Alterations in Patients With Thyroid Colloid Nodule

Conclusion: Our results reveal prominent cytoplasmic VDR expression, suggesting a distinct distribution pattern and offering valuable insights into its potential role in colloid nodules. VDR expression increases with increasing size and number of nodules. Regarding FokI genotypes, TT genotype was le...

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Main Authors: Mariwan F. Abdalfatah, Abdullah A. Shareef, Lana S. Saleh, Mustafa F. Rajab, Shukur W. Smail, Saman S. Abdulla, Harem Khdir Awla, Rivan H. Ishaac, Kazhal S. Ibrahim, Mazyar J. Ahmed, Fairuz A. Kakasur, Khder Hussein Rasul
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/ancp/6796922
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Summary:Conclusion: Our results reveal prominent cytoplasmic VDR expression, suggesting a distinct distribution pattern and offering valuable insights into its potential role in colloid nodules. VDR expression increases with increasing size and number of nodules. Regarding FokI genotypes, TT genotype was less likely to develop colloid nodule. These findings contribute to our understanding of cellular characteristics of this condition and may have implications for future research and clinical management.
ISSN:2210-7185

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