An unconventional T cell nexus drives HCK-mediated chronic obstructive pulmonary disease in miceResearch in context

An unconventional T cell nexus drives HCK-mediated chronic obstructive pulmonary disease in miceResearch in context

Summary: Background: Chronic obstructive pulmonary disease (COPD) is a heterogeneous inflammatory lung disease leading to progressive, destructive lung function decline, disability and death, and it is refractory to all current treatments. Haematopoietic cell kinase (HCK) is a druggable SRC-family...

Full description

Saved in:
Bibliographic Details
Main Authors: Amy T. Hsu, Robert J.J. O'Donoghue, Evelyn Tsantikos, Timothy A. Gottschalk, Jessica G. Borger, Nicholas A. Gherardin, Calvin Xu, Hui-Fern Koay, Dale I. Godfrey, Matthias Ernst, Gary P. Anderson, Margaret L. Hibbs
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:EBioMedicine
Subjects:
Constitutive HCK activation
Chronic obstructive pulmonary disease
Mucus-producing goblet cells
IL-17A/G-CSF axis
Granulocytes
Unconventional T cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396425001513
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2352396425001513

Similar Items