Trimetazidine: Activating AMPK Signal to Ameliorate Coronary Microcirculation Dysfunction after Myocardial Infarction

Trimetazidine: Activating AMPK Signal to Ameliorate Coronary Microcirculation Dysfunction after Myocardial Infarction

Background: Myocardial ischemia-reperfusion (I/R) injury and coronary microcirculation dysfunction (CMD) are observed in patients with myocardial infarction after vascular recanalization. The antianginal drug trimetazidine has been demonstrated to exert a protective effect in myoc...

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Bibliographic Details
Main Authors: Xiaolong Qu, Pan Yang, Li Jiao, Yuehui Yin
Format: Article
Language:English
Published: IMR Press 2025-01-01
Series:Frontiers in Bioscience-Landmark
Subjects:
trimetazidine
coronary microcirculation dysfunction
myocardial infarction
ampk signal
Online Access:https://www.imrpress.com/journal/FBL/30/1/10.31083/FBL25565
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