Conserved role of spike S2 domain N-glycosylation across betacoronaviruses
Abstract Besides acting as an immunological shield, the N-glycans of SARS-CoV-2 are also critical for viral life cycle. As the S2 subunit of spike is highly conserved across betacoronaviruses, we determined the functional significance of the five ‘stem N-glycans’ located in S2 between N1098-N1194. S...
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Main Authors: | Qi Yang, Anju Kelkar, Balaji Manicassamy, Sriram Neelamegham |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | npj Viruses |
Online Access: | https://doi.org/10.1038/s44298-024-00085-7 |
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