Low-Level Laser Therapy for Temporomandibular Disorders: A Systematic Review with Meta-Analysis
Objectives. We systematically reviewed randomized controlled trials (RCTs) of the effect of low-level laser therapy (LLLT) versus placebo in patients with temporomandibular disorder (TMD). Methods. A systematic search of multiple online sources electronic databases was undertaken. The methodological...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/2018/4230583 |
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| author | Gang-Zhu Xu Jie Jia Lin Jin Jia-Heng Li Zhan-Yue Wang Dong-Yuan Cao |
| author_facet | Gang-Zhu Xu Jie Jia Lin Jin Jia-Heng Li Zhan-Yue Wang Dong-Yuan Cao |
| author_sort | Gang-Zhu Xu |
| collection | DOAJ |
| description | Objectives. We systematically reviewed randomized controlled trials (RCTs) of the effect of low-level laser therapy (LLLT) versus placebo in patients with temporomandibular disorder (TMD). Methods. A systematic search of multiple online sources electronic databases was undertaken. The methodological quality of each included study was assessed using the modified Jadad scale, and the quality of evidence was evaluated using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system. Results. A total of 31 RCTs were included. Total modified Jadad scale scores showed that the methodological quality was high in 30 studies and low in 1 study. Combining data from all clinically heterogeneous studies revealed positive effects of LLLT on pain relief, regardless of the visual analogue scale (VAS) score or the change of VAS score between the baseline and the final follow-up time point, while dosage analyses showed discrepant results about the effects of high or low doses for patients with TMD. Follow-up analyses showed that LLLT significantly reduced pain at the short-term follow-up. Temporomandibular joint function outcomes indicated that the overall effect favored LLLT over placebo. Conclusion. This systematic review suggests that LLLT effectively relieves pain and improves functional outcomes in patients with TMD. |
| format | Article |
| id | doaj-art-a7d583cf26374b0abde6ed459db9a2f5 |
| institution | Kabale University |
| issn | 1203-6765 1918-1523 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pain Research and Management |
| spelling | doaj-art-a7d583cf26374b0abde6ed459db9a2f52025-02-03T01:00:52ZengWileyPain Research and Management1203-67651918-15232018-01-01201810.1155/2018/42305834230583Low-Level Laser Therapy for Temporomandibular Disorders: A Systematic Review with Meta-AnalysisGang-Zhu Xu0Jie Jia1Lin Jin2Jia-Heng Li3Zhan-Yue Wang4Dong-Yuan Cao5Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, Research Center of Stomatology, College of Stomatology, Xi’an Jiaotong University, Xi’an, Shaanxi, ChinaDepartment of Psychiatry, Xi’an Mental Health Center, Xi’an, Shaanxi, ChinaDepartment of Neurosurgery, First Affiliated Hospital of Xi’an Medical University, Xi’an, Shaanxi, ChinaKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, Research Center of Stomatology, College of Stomatology, Xi’an Jiaotong University, Xi’an, Shaanxi, ChinaKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, Research Center of Stomatology, College of Stomatology, Xi’an Jiaotong University, Xi’an, Shaanxi, ChinaKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, Research Center of Stomatology, College of Stomatology, Xi’an Jiaotong University, Xi’an, Shaanxi, ChinaObjectives. We systematically reviewed randomized controlled trials (RCTs) of the effect of low-level laser therapy (LLLT) versus placebo in patients with temporomandibular disorder (TMD). Methods. A systematic search of multiple online sources electronic databases was undertaken. The methodological quality of each included study was assessed using the modified Jadad scale, and the quality of evidence was evaluated using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system. Results. A total of 31 RCTs were included. Total modified Jadad scale scores showed that the methodological quality was high in 30 studies and low in 1 study. Combining data from all clinically heterogeneous studies revealed positive effects of LLLT on pain relief, regardless of the visual analogue scale (VAS) score or the change of VAS score between the baseline and the final follow-up time point, while dosage analyses showed discrepant results about the effects of high or low doses for patients with TMD. Follow-up analyses showed that LLLT significantly reduced pain at the short-term follow-up. Temporomandibular joint function outcomes indicated that the overall effect favored LLLT over placebo. Conclusion. This systematic review suggests that LLLT effectively relieves pain and improves functional outcomes in patients with TMD.http://dx.doi.org/10.1155/2018/4230583 |
| spellingShingle | Gang-Zhu Xu Jie Jia Lin Jin Jia-Heng Li Zhan-Yue Wang Dong-Yuan Cao Low-Level Laser Therapy for Temporomandibular Disorders: A Systematic Review with Meta-Analysis Pain Research and Management |
| title | Low-Level Laser Therapy for Temporomandibular Disorders: A Systematic Review with Meta-Analysis |
| title_full | Low-Level Laser Therapy for Temporomandibular Disorders: A Systematic Review with Meta-Analysis |
| title_fullStr | Low-Level Laser Therapy for Temporomandibular Disorders: A Systematic Review with Meta-Analysis |
| title_full_unstemmed | Low-Level Laser Therapy for Temporomandibular Disorders: A Systematic Review with Meta-Analysis |
| title_short | Low-Level Laser Therapy for Temporomandibular Disorders: A Systematic Review with Meta-Analysis |
| title_sort | low level laser therapy for temporomandibular disorders a systematic review with meta analysis |
| url | http://dx.doi.org/10.1155/2018/4230583 |
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