Chemically defined and xeno-free media enables the derivation of human extended pluripotent stem cell lines from discarded blastocysts with a high efficiency
Abstract Human extended pluripotent stem cells (hEPS) had been reported to be derived from discarded blastocysts, whereas the derivation method of hEPS cells was extremely complex in this protocol with feeder and animal serum conditions, which also limited the safety and homogeneity of hEPS. Here, w...
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| Main Authors: | Zhuran Zhao, Xi Chen, Shan Wang, Min Fu, Huan Shen, Jiayu Li, Jun Xu, Jiong Qin, Cheng Shi |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
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| Series: | Cell & Bioscience |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13578-025-01410-0 |
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