A benchmark study of compression software for human short-read sequence data

A benchmark study of compression software for human short-read sequence data

Abstract Efficient data compression technologies are crucial to reduce the cost of long-term storage and file transfer in whole genome sequencing studies. This study benchmarked four specialized compression tools developed for paired-end fastq.gz files DRAGEN ORA 4.3.4 (ORA), Genozip 15.0.62, repaq...

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Bibliographic Details
Main Authors: Raphael O. Betschart, Felix Thalén, Stefan Blankenberg, Martin Zoche, Tanja Zeller, Andreas Ziegler
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
BAM
CRAM
DNA sequencing
FASTQ
GVCF
Illumina sequencing
Online Access:https://doi.org/10.1038/s41598-025-00491-8
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https://doi.org/10.1038/s41598-025-00491-8

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