Roles of hypoxia inducible factors in viral infection: Are they a potential therapeutic target?

Roles of hypoxia inducible factors in viral infection: Are they a potential therapeutic target?

As a crucial nuclear transcription factor, hypoxia-inducible factor (HIF) serves essential functions in mediating cellular responses to hypoxic stress. Through oxygen-sensing mechanisms, HIF initiates downstream signaling cascades that coordinate metabolic reprogramming, immune modulation, and oncog...

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Bibliographic Details
Main Authors: Sikai Jia, Shuo Pan, Zhiyun Gao, Hongxiu Qiao, Yan Zhao, Xia Chuai, Jian Li
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Virulence
Subjects:
Hypoxia inducible factor
virus infection
immunization
hypoxia
normoxia
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2025.2546680
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