Computer analysis of regulation of hepatocarcinoma marker genes hypermethylated by HCV proteins

Computer analysis of regulation of hepatocarcinoma marker genes hypermethylated by HCV proteins

Hepatitis C virus (HCV) is a risk factor that leads to hepatocellular carcinoma (HCC) development. Epigenetic changes are known to play an important role in the molecular genetic mechanisms of virus-induced oncogenesis. Aber rant DNA methylation is a mediator of epigenetic changes that are closely a...

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Main Authors: E. A. Antropova, T. M. Khlebodarova, P. S. Demenkov, A. S. Venzel, N. V. Ivanisenko, A.  D.  Gavrilenko, T.  V. Ivanisenko, A. V. Adamovskaya, P. M. Revva, I. N. Lavrik, V. A. Ivanisenko
Format: Article
Language:English
Published: Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2023-01-01
Series:Вавиловский журнал генетики и селекции
Subjects:
hepatocellular carcinoma
hepatitis c virus
expression regulation
methylation
regulatory pathways
gene networks
bioinformatics
Online Access:https://vavilov.elpub.ru/jour/article/view/3574
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