Two Cases of Pituitary Stalk Interruption Syndrome in Syrian Children

Pituitary stalk interruption syndrome (PSIS) is an extremely rare cause of growth failure and delayed puberty. It can be diagnosed by magnetic resonance imaging (MRI) of the hypothalamus and pituitary gland, showing an ectopic or absent posterior pituitary, an absent or interrupted pituitary stalk,...

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Main Authors: Ibrahim Alali, Reem Saad, Younes Kabalan
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2020/2039649
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author Ibrahim Alali
Reem Saad
Younes Kabalan
author_facet Ibrahim Alali
Reem Saad
Younes Kabalan
author_sort Ibrahim Alali
collection DOAJ
description Pituitary stalk interruption syndrome (PSIS) is an extremely rare cause of growth failure and delayed puberty. It can be diagnosed by magnetic resonance imaging (MRI) of the hypothalamus and pituitary gland, showing an ectopic or absent posterior pituitary, an absent or interrupted pituitary stalk, or small anterior pituitary, in combination with growth hormone or other pituitary hormone deficiencies. The exact etiology of PSIS is unknown. In this article, we describe two cases of PSIS in Syria which are, as far as we know, the first published cases.
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institution Kabale University
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2090-651X
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publishDate 2020-01-01
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series Case Reports in Endocrinology
spelling doaj-art-a76f3779e6f04569875aa2ada9f24aaf2025-02-03T01:05:09ZengWileyCase Reports in Endocrinology2090-65012090-651X2020-01-01202010.1155/2020/20396492039649Two Cases of Pituitary Stalk Interruption Syndrome in Syrian ChildrenIbrahim Alali0Reem Saad1Younes Kabalan2Al-Assad University Hospital, Damascus University, Damascus, SyriaAl-Mowassat University Hospital, Damascus University, Damascus, SyriaAl-Assad University Hospital, Damascus University, Damascus, SyriaPituitary stalk interruption syndrome (PSIS) is an extremely rare cause of growth failure and delayed puberty. It can be diagnosed by magnetic resonance imaging (MRI) of the hypothalamus and pituitary gland, showing an ectopic or absent posterior pituitary, an absent or interrupted pituitary stalk, or small anterior pituitary, in combination with growth hormone or other pituitary hormone deficiencies. The exact etiology of PSIS is unknown. In this article, we describe two cases of PSIS in Syria which are, as far as we know, the first published cases.http://dx.doi.org/10.1155/2020/2039649
spellingShingle Ibrahim Alali
Reem Saad
Younes Kabalan
Two Cases of Pituitary Stalk Interruption Syndrome in Syrian Children
Case Reports in Endocrinology
title Two Cases of Pituitary Stalk Interruption Syndrome in Syrian Children
title_full Two Cases of Pituitary Stalk Interruption Syndrome in Syrian Children
title_fullStr Two Cases of Pituitary Stalk Interruption Syndrome in Syrian Children
title_full_unstemmed Two Cases of Pituitary Stalk Interruption Syndrome in Syrian Children
title_short Two Cases of Pituitary Stalk Interruption Syndrome in Syrian Children
title_sort two cases of pituitary stalk interruption syndrome in syrian children
url http://dx.doi.org/10.1155/2020/2039649
work_keys_str_mv AT ibrahimalali twocasesofpituitarystalkinterruptionsyndromeinsyrianchildren
AT reemsaad twocasesofpituitarystalkinterruptionsyndromeinsyrianchildren
AT youneskabalan twocasesofpituitarystalkinterruptionsyndromeinsyrianchildren