Regulation of Sulfotransferase and UDP-Glucuronosyltransferase Gene Expression by the PPARs
During phase II metabolism, a substrate is rendered more hydrophilic through the covalent attachment of an endogenous molecule. The cytosolic sulfotransferase (SULT) and UDP-glucuronosyltransferase (UGT) families of enzymes account for the majority of phase II metabolism in humans and animals. In ge...
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Main Authors: | Melissa Runge-Morris, Thomas A. Kocarek |
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Format: | Article |
Language: | English |
Published: |
Wiley
2009-01-01
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Series: | PPAR Research |
Online Access: | http://dx.doi.org/10.1155/2009/728941 |
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