Regulation of Sulfotransferase and UDP-Glucuronosyltransferase Gene Expression by the PPARs

During phase II metabolism, a substrate is rendered more hydrophilic through the covalent attachment of an endogenous molecule. The cytosolic sulfotransferase (SULT) and UDP-glucuronosyltransferase (UGT) families of enzymes account for the majority of phase II metabolism in humans and animals. In ge...

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Bibliographic Details
Main Authors: Melissa Runge-Morris, Thomas A. Kocarek
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2009/728941
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