МATHEMATICAL MODELING OF ETHANOL AND LACTIC ACID BIOSYNTHESIS BY THERMOPHILIC Geobacillus BACTERIA
A mathematical model of the ethanol and lactic acid biosynthesis in the cells of Geobacillus spp. developed and adapted to the available experimental data is presented. It is shown that the mathematical model allows in silico design of genetic engineering experiments with the Geobacillus spp. bacter...
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| Format: | Article |
| Language: | English |
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Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders
2015-01-01
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| Series: | Вавиловский журнал генетики и селекции |
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| Online Access: | https://vavilov.elpub.ru/jour/article/view/193 |
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| author | M. A. Nuriddinov F. V. Kazantsev A. S. Rozanov K. N. Kozlov S. E. Peltek I. R. Akberdin N. A. Kolchanov |
| author_facet | M. A. Nuriddinov F. V. Kazantsev A. S. Rozanov K. N. Kozlov S. E. Peltek I. R. Akberdin N. A. Kolchanov |
| author_sort | M. A. Nuriddinov |
| collection | DOAJ |
| description | A mathematical model of the ethanol and lactic acid biosynthesis in the cells of Geobacillus spp. developed and adapted to the available experimental data is presented. It is shown that the mathematical model allows in silico design of genetic engineering experiments with the Geobacillus spp. bacterium and prediction of the dynamics of changes in synthesized ethanol and lactic acid concentrations depending on the molecular manipulations with the activity of enzymes of the metabolic system. |
| format | Article |
| id | doaj-art-a7394515eb2745b48dc0c680fcb5f47d |
| institution | Kabale University |
| issn | 2500-3259 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders |
| record_format | Article |
| series | Вавиловский журнал генетики и селекции |
| spelling | doaj-art-a7394515eb2745b48dc0c680fcb5f47d2025-02-01T09:58:00ZengSiberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and BreedersВавиловский журнал генетики и селекции2500-32592015-01-01174/1686704177МATHEMATICAL MODELING OF ETHANOL AND LACTIC ACID BIOSYNTHESIS BY THERMOPHILIC Geobacillus BACTERIAM. A. Nuriddinov0F. V. Kazantsev1A. S. Rozanov2K. N. Kozlov3S. E. Peltek4I. R. Akberdin5N. A. Kolchanov6Institute of Cytology and Genetics SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaSt-Petersburg State Polytechnicol university, St-Petersburg, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, Russia Novosibirsk National Research State University, Novosibirsk, RussiaA mathematical model of the ethanol and lactic acid biosynthesis in the cells of Geobacillus spp. developed and adapted to the available experimental data is presented. It is shown that the mathematical model allows in silico design of genetic engineering experiments with the Geobacillus spp. bacterium and prediction of the dynamics of changes in synthesized ethanol and lactic acid concentrations depending on the molecular manipulations with the activity of enzymes of the metabolic system.https://vavilov.elpub.ru/jour/article/view/193mathematical modelkinetic datalactic acidbioethanolgeobacillus |
| spellingShingle | M. A. Nuriddinov F. V. Kazantsev A. S. Rozanov K. N. Kozlov S. E. Peltek I. R. Akberdin N. A. Kolchanov МATHEMATICAL MODELING OF ETHANOL AND LACTIC ACID BIOSYNTHESIS BY THERMOPHILIC Geobacillus BACTERIA Вавиловский журнал генетики и селекции mathematical model kinetic data lactic acid bioethanol geobacillus |
| title | МATHEMATICAL MODELING OF ETHANOL AND LACTIC ACID BIOSYNTHESIS BY THERMOPHILIC Geobacillus BACTERIA |
| title_full | МATHEMATICAL MODELING OF ETHANOL AND LACTIC ACID BIOSYNTHESIS BY THERMOPHILIC Geobacillus BACTERIA |
| title_fullStr | МATHEMATICAL MODELING OF ETHANOL AND LACTIC ACID BIOSYNTHESIS BY THERMOPHILIC Geobacillus BACTERIA |
| title_full_unstemmed | МATHEMATICAL MODELING OF ETHANOL AND LACTIC ACID BIOSYNTHESIS BY THERMOPHILIC Geobacillus BACTERIA |
| title_short | МATHEMATICAL MODELING OF ETHANOL AND LACTIC ACID BIOSYNTHESIS BY THERMOPHILIC Geobacillus BACTERIA |
| title_sort | мathematical modeling of ethanol and lactic acid biosynthesis by thermophilic geobacillus bacteria |
| topic | mathematical model kinetic data lactic acid bioethanol geobacillus |
| url | https://vavilov.elpub.ru/jour/article/view/193 |
| work_keys_str_mv | AT manuriddinov mathematicalmodelingofethanolandlacticacidbiosynthesisbythermophilicgeobacillusbacteria AT fvkazantsev mathematicalmodelingofethanolandlacticacidbiosynthesisbythermophilicgeobacillusbacteria AT asrozanov mathematicalmodelingofethanolandlacticacidbiosynthesisbythermophilicgeobacillusbacteria AT knkozlov mathematicalmodelingofethanolandlacticacidbiosynthesisbythermophilicgeobacillusbacteria AT sepeltek mathematicalmodelingofethanolandlacticacidbiosynthesisbythermophilicgeobacillusbacteria AT irakberdin mathematicalmodelingofethanolandlacticacidbiosynthesisbythermophilicgeobacillusbacteria AT nakolchanov mathematicalmodelingofethanolandlacticacidbiosynthesisbythermophilicgeobacillusbacteria |