Lipid Histiocytosis of the Gallbladder Neck Lymph Node

Lipid histiocytosis of the gallbladder neck lymph node is rarely reported nowadays. Two obese patients presented with gallbladder lithiasis detected on CT scan. The treatment consisted in coelioscopic cholecystectomy. Microscopy revealed subacute/chronic lithiasic cholecystitis and foci of vacuolate...

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Main Authors: Adriana Handra-Luca, Mohamed Habib Ben Romdhane, Beate Katharina Straub
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2016/1061507
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author Adriana Handra-Luca
Mohamed Habib Ben Romdhane
Beate Katharina Straub
author_facet Adriana Handra-Luca
Mohamed Habib Ben Romdhane
Beate Katharina Straub
author_sort Adriana Handra-Luca
collection DOAJ
description Lipid histiocytosis of the gallbladder neck lymph node is rarely reported nowadays. Two obese patients presented with gallbladder lithiasis detected on CT scan. The treatment consisted in coelioscopic cholecystectomy. Microscopy revealed subacute/chronic lithiasic cholecystitis and foci of vacuolated cells in the gallbladder neck lymph node. These cells were positive for CD68, CD31, S100 protein, and adipophilin and negative for cytokeratin and Alcian blue. In conclusion, we report lymph node lipid histiocytosis diagnosed microscopically after cholecystectomy. While such lesions may remain unidentified on imaging procedures, the microscopic analysis may require special stains and immunohistochemistry for ruling out adenocarcinoma metastasis.
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institution Kabale University
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series Case Reports in Pathology
spelling doaj-art-a6e8c2f988094da08fb5a8bc78c8598a2025-02-03T01:22:11ZengWileyCase Reports in Pathology2090-67812090-679X2016-01-01201610.1155/2016/10615071061507Lipid Histiocytosis of the Gallbladder Neck Lymph NodeAdriana Handra-Luca0Mohamed Habib Ben Romdhane1Beate Katharina Straub2APHP, Service d’Anatomie Pathologique, Bobigny, FranceAPHP, Service de Radiologie, Bobigny, FranceInstitute of Pathology, University Clinic Heidelberg, Heidelberg, GermanyLipid histiocytosis of the gallbladder neck lymph node is rarely reported nowadays. Two obese patients presented with gallbladder lithiasis detected on CT scan. The treatment consisted in coelioscopic cholecystectomy. Microscopy revealed subacute/chronic lithiasic cholecystitis and foci of vacuolated cells in the gallbladder neck lymph node. These cells were positive for CD68, CD31, S100 protein, and adipophilin and negative for cytokeratin and Alcian blue. In conclusion, we report lymph node lipid histiocytosis diagnosed microscopically after cholecystectomy. While such lesions may remain unidentified on imaging procedures, the microscopic analysis may require special stains and immunohistochemistry for ruling out adenocarcinoma metastasis.http://dx.doi.org/10.1155/2016/1061507
spellingShingle Adriana Handra-Luca
Mohamed Habib Ben Romdhane
Beate Katharina Straub
Lipid Histiocytosis of the Gallbladder Neck Lymph Node
Case Reports in Pathology
title Lipid Histiocytosis of the Gallbladder Neck Lymph Node
title_full Lipid Histiocytosis of the Gallbladder Neck Lymph Node
title_fullStr Lipid Histiocytosis of the Gallbladder Neck Lymph Node
title_full_unstemmed Lipid Histiocytosis of the Gallbladder Neck Lymph Node
title_short Lipid Histiocytosis of the Gallbladder Neck Lymph Node
title_sort lipid histiocytosis of the gallbladder neck lymph node
url http://dx.doi.org/10.1155/2016/1061507
work_keys_str_mv AT adrianahandraluca lipidhistiocytosisofthegallbladdernecklymphnode
AT mohamedhabibbenromdhane lipidhistiocytosisofthegallbladdernecklymphnode
AT beatekatharinastraub lipidhistiocytosisofthegallbladdernecklymphnode