Reciprocal regulation between DNMT3A/3B and microRNAs miRs-299-3p/-30e is a causal factor for the downregulation of microRNAs targeting androgen receptor in prostate cancer
Background: Promoter hypermethylation is one of the events that downregulate microRNAs (miRNA), resulting in the differential expression of genes implicated in the progression of cancer. We previously reported that microRNAs (miRNA)-299-3p and −30e target androgen receptor (AR) and are downregulated...
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Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-02-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844025003287 |
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