A Case of Anterior Spinal Artery Syndrome Caused by Streptococcus mitis Endocarditis

Background. Infectious endocarditis (IE) typically occurs in the setting of intravenous drug use, prosthetic heart valves, or rheumatic heart disease. However, there are a few reports of IE occurring in the setting of immunosuppression secondary to cancer and/or chemotherapy. Here, we present a case...

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Main Authors: Aria Mahtabfar, Hamoon Eshraghi, Melroy D’Souza, William Berrigan, Kathleen Casey
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2018/9658120
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author Aria Mahtabfar
Hamoon Eshraghi
Melroy D’Souza
William Berrigan
Kathleen Casey
author_facet Aria Mahtabfar
Hamoon Eshraghi
Melroy D’Souza
William Berrigan
Kathleen Casey
author_sort Aria Mahtabfar
collection DOAJ
description Background. Infectious endocarditis (IE) typically occurs in the setting of intravenous drug use, prosthetic heart valves, or rheumatic heart disease. However, there are a few reports of IE occurring in the setting of immunosuppression secondary to cancer and/or chemotherapy. Here, we present a case of a cancer patient who developed anterior spinal artery (ASA) syndrome secondary to a septic embolus from IE. Case Presentation. A 78-year-old male with a history of gastroesophageal cancer treated with chemotherapy and radiation presented to the hospital after a fall at home. He reported experiencing dyspnea and orthopnea for two weeks prior to presentation. In the ED, his vital signs were stable, and his examination was significant for a flaccid paralysis of the right lower extremity. Diagnosis of septic emboli secondary to IE was made after the echocardiogram showed the presence of vegetations on the aortic valve, blood cultures were positive for Streptococcus mitis, and thoracic spine MRI was indicative of an infarction at T10. Discussion. This case highlights the presence of IE in the setting of cancer and chemotherapy. Although cancer is a rare cause of IE, clinicians must maintain a high index of suspicion in order to minimize the sequelae of IE.
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spelling doaj-art-a69bfbf85e234ea49e9ba052ca6b390f2025-02-03T01:07:15ZengWileyCase Reports in Medicine1687-96271687-96352018-01-01201810.1155/2018/96581209658120A Case of Anterior Spinal Artery Syndrome Caused by Streptococcus mitis EndocarditisAria Mahtabfar0Hamoon Eshraghi1Melroy D’Souza2William Berrigan3Kathleen Casey4Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USARutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USARutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USADepartment of Medicine, Jersey Shore University Medical Center, Neptune, NJ, USADepartment of Infectious Disease, Jersey Shore University Medical Center, Neptune, NJ, USABackground. Infectious endocarditis (IE) typically occurs in the setting of intravenous drug use, prosthetic heart valves, or rheumatic heart disease. However, there are a few reports of IE occurring in the setting of immunosuppression secondary to cancer and/or chemotherapy. Here, we present a case of a cancer patient who developed anterior spinal artery (ASA) syndrome secondary to a septic embolus from IE. Case Presentation. A 78-year-old male with a history of gastroesophageal cancer treated with chemotherapy and radiation presented to the hospital after a fall at home. He reported experiencing dyspnea and orthopnea for two weeks prior to presentation. In the ED, his vital signs were stable, and his examination was significant for a flaccid paralysis of the right lower extremity. Diagnosis of septic emboli secondary to IE was made after the echocardiogram showed the presence of vegetations on the aortic valve, blood cultures were positive for Streptococcus mitis, and thoracic spine MRI was indicative of an infarction at T10. Discussion. This case highlights the presence of IE in the setting of cancer and chemotherapy. Although cancer is a rare cause of IE, clinicians must maintain a high index of suspicion in order to minimize the sequelae of IE.http://dx.doi.org/10.1155/2018/9658120
spellingShingle Aria Mahtabfar
Hamoon Eshraghi
Melroy D’Souza
William Berrigan
Kathleen Casey
A Case of Anterior Spinal Artery Syndrome Caused by Streptococcus mitis Endocarditis
Case Reports in Medicine
title A Case of Anterior Spinal Artery Syndrome Caused by Streptococcus mitis Endocarditis
title_full A Case of Anterior Spinal Artery Syndrome Caused by Streptococcus mitis Endocarditis
title_fullStr A Case of Anterior Spinal Artery Syndrome Caused by Streptococcus mitis Endocarditis
title_full_unstemmed A Case of Anterior Spinal Artery Syndrome Caused by Streptococcus mitis Endocarditis
title_short A Case of Anterior Spinal Artery Syndrome Caused by Streptococcus mitis Endocarditis
title_sort case of anterior spinal artery syndrome caused by streptococcus mitis endocarditis
url http://dx.doi.org/10.1155/2018/9658120
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